enVVeno Medical Corp

Based in Irvine, California, enVVeno Medical Corporation operates as a clinical-stage medical technology company. Its core mission revolves around pioneering advanced bioprosthetic tissue solutions aimed at elevating the standard of care for patients suffering from venous diseases. The company's flagship innovation is the VenoValve, a surgical implant engineered to address Chronic Venous Insufficiency (CVI). This device is surgically placed within the femoral vein, where it acts as a unidirectional valve, effectively re-establishing healthy blood flow in the leg. Complementing this, enVVeno is also developing enVVe, a non-invasive, transcatheter-delivered venous valve replacement, also intended for CVI treatment. Founded in 1999, the company underwent a name change in October 2021, transitioning from its former identity as Hancock Jaffe Laboratories, Inc.