XNAS
CABA
Market cap317mUSD
Oct 08, Last price
1.95USD
1D
-1.02%
1Q
-34.45%
IPO
-80.52%
Name
Cabaletta Bio Inc
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Profile
Cabaletta Bio, Inc. is a biotechnology firm in the clinical development stage, specializing in the invention and advancement of sophisticated engineered T cell therapies. Its core mission is to treat autoimmune diseases where B cells are implicated in producing harmful autoantibodies. The company's unique chimeric autoantibody receptor (CAAR) T cell platform is engineered to precisely target and eradicate these specific disease-causing B cells. Leading its pipeline is DSG3-CAART, which is currently in Phase I clinical trials. This candidate is being assessed for efficacy in two distinct conditions: mucosal pemphigus vulgaris, an autoimmune blistering skin disorder, and Hemophilia A in patients exhibiting Factor VIII alloantibodies. Cabaletta's broader product candidate portfolio also includes MuSK-CAART, a preclinical asset aimed at a particular subset of myasthenia gravis patients; FVIII-CAART, in the discovery phase for another subgroup of Hemophilia A sufferers; and DSG3/1-CAART, also a discovery-stage program, designed for mucocutaneous pemphigus vulgaris. The company maintains strategic alliances, including a collaboration with the University of Pennsylvania and a research pact with The Regents of the University of California. Founded in 2017 as Tycho Therapeutics, Inc., it adopted the name Cabaletta Bio, Inc. in August 2018 and is based in Philadelphia, Pennsylvania.
Key people
Anup Marda
Chief Financial Officer · since 2021
Gwendolyn Binder-Scholl
President - Science and Technology · since 2022
David Chang
Chief Medical Officer · since 2019
Arun Das
Chief Business Officer · since 2022
Michael Gerard
General Counsel, Secretary · since 2021
Steven Nichtberger
Chief Executive Officer, President, Chairman of the Board, Co-Founder · since 2017
Catherine Bollard
Independent Director · since 2019
Independent Director · since 2021
Richard Henriques
Independent Director · since 2019
Mark Simon
Independent Director · since 2018
Independent Director · since 2023
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