XNAS
ARWR
Market cap8.56bUSD
Oct 08, Last price
60.74USD
1D
-1.20%
1Q
-20.50%
Jan 2017
3,818.71%
Name
Arrowhead Pharmaceuticals Inc
Chart & performance
P/E
—
P/S
10.31
EPS
—
Div yield, %
—
Shrs. gr., 5y
5.84%
Rev. gr., 5y
56.63%
Revenues
829m
+23,258.15%
Net income
-2m
L-99.73%
CFO
180m
P
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Profile
Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead's development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.
Key people
Christopher Anzalone
Chairman of the Board, President, Chief Executive Officer · since 2023
Daniel Apel
Chief Financial Officer · since 2025
James Hamilton
Chief of Discovery and Translational Medicine · since 2023
Patrick O'Brien
Chief Operating Officer, Company Secretary · since 2025
Lead Independent Director · since 2023
Independent Director · since 2010
Hongbo Lu
Independent Director · since 2024
Independent Director · since 2020
Independent Director · since 2023
Victoria Vakiener
Independent Director · since 2022
Legal address
C/O PARACORP INCORPORATED
2140 S DUPONT HWY
CAMDEN, DE 19934
US
2140 S DUPONT HWY
CAMDEN, DE 19934
US
Headquarters
177 East Colorado Boulevard
Suite 700
Pasadena, CA 91105
US
Suite 700
Pasadena, CA 91105
US
Previous name
Arrowhead Research Corporation
Valuation
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